Can radical prostatectomy shortly after prostate biopsy affect intra-operative and postoperative outcomes?

differences between the three groups. All statistical analyses were conducted on Microsoft Excel 2010 platform version 10.1. P <0.05 was considered statistically significant. −2. The number of biopsy cores was 10.4 ± 3.0. No significant difference was noted between the three groups when comparing age, preoperative PSA level, prostate volume, BMI, biopsy number, clinical stage, and Gleason grade. In cases of extended biopsy (more than 10 cores obtained), operative time was longer (232.4 min vs 214.9 min), but no clinical significance was showed on multivariate analysis. An increasing EBL was associated with an elevated BMI in all groups (P < 0.001). Longer OD times were associated with an elevated BMI (P < 0.001) and Gleason grade (P = 0.003). Also, positive surgical margins were associated with pathologic stage (P = 0.006), PSA level (P < 0.002), Gleason grade (P = 0.003), and extracapsular extension (P < 0.002). Finally, urinary continence was associated with patient age (P = 0.001). Both univariate and multivariate analyses, however, failed to show that the interval from biopsy to surgery had any significant relations with PSM, HS, and postoperative urinary continence. There were no statistically significant differences in terms of complication rate between three groups (P = 0.325). Fifty patients (10.5%) developed complications, including pelvic hematoma in 4.9% (23/473), transfer to intensive care for cardiac and respiratory monitoring in 2.3% (11/473), and lymphocele formation in 3.4% (16/473). No patient died. Prostate cancer is a major cause of morbidity among men worldwide. It is generally considered a relatively slow-growing malignancy. 1 The delay for pretreatment diagnostics or psychological reasons between diagnosis and active therapy of PCa is often common. 2 The prostate biopsy is the most common used procedure to detect PCa. During the last decade, the number of needle biopsy cores taken has increased, as have biopsies in younger patients and repeated biopsies. 3 Traditionally, urologists recommend an interval of >4–6 weeks after transrectal prostate biopsy before RP, to allow time Dear Editor, We retrospectively evaluated the patients who underwent radical prostatectomy (RP) for prostate cancer (PCa) if the interval between PB and RP had any impact on immediate outcomes after surgery treatment. The study population comprised 473 patients with localized or locally advanced PCa (clinical stage T1c to T3c) diagnosed via a transrectal ultrasound-guided prostate biopsy (TPB) conducted by three urologists. The patients who underwent RP (109 with laparoscopic technique and 364 with open technique) …